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doi: 10.1245/s10434-015-4388-4 6 BauerKSchroederMPorzsoltFHenne-BrunsD
ATTAIN-1 (NCT05869903) is a Phase 3, 72-week, randomized, double-blind, placebo-controlled trial comparing the efficacy and safety of Foundayo 5.5 mg, 9 mg and 17.2 mg as a monotherapy to placebo in adults with obesity, or overweight with at least one of the following comorbidities: hypertension, dyslipidemia, obstructive sleep apnea or cardiovascular disease, who did not have diabetes
If a person carries a GIPR variant that affects GIP receptor function, the combined stimulation of both receptors may produce a stronger nausea response than GLP-1 stimulation alone
21 For instance, systemic iron is bound primarily to the TF and cellular iron uptake is mediated by TF and its receptor TFR1
