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Accessed 8/10/2014
Cancer cell biology research examining IGF1R-driven proliferation often uses LR3 as a standard reagent precisely because the dose-response across a multi-day proliferation assay is more interpretable when the ligand is stable in the media
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TB-500 is studied primarily for its cellular migration-promoting, stem cell-mobilising, actin-sequestering, and anti-apoptotic properties across wound healing, cardiac, CNS, and musculoskeletal models
However, this doesnt mean supplementation is ineffective
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