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Some animal models have provided evidence suggesting that GLP1 is a physiologically relevant natriuretic factor that contributes to sodium balance, partly through the tonal modulation of the activity of sodium-hydrogen exchanger isoform 3 (NHE3) in the brush border of the proximal convoluted tubule 23 , 24
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Several GLP-1 receptor agonists are FDA-approved for type 2 diabetes management and, in some cases, chronic weight management
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