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Neither compound is approved by the FDA for human or veterinary therapeutic use
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In Figure 4 It was observed that, compared to the normal architecture and regular pattern of hepatocytes with active vesicular nuclei in G1 (Normal control), the liver of G2 (MTX) showed central vein dilation and congestion (a in Figure 4B), Focal cell necrosis, hepatocyte nuclei of many cells are dark stained, and small apoptosis was also observed
1743 The toxic actions of beta-blockers appear to be related to properties such as membrane depressant activity and possibly due to actions on beta-adrenoceptors distinct from those in the cardiovascular system
