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doi:10.1152/ajpregu.00360.2001

Nat Rev Cardiol

This is why dermatologist-supervised IV therapy is non-negotiable

Decreased NAD + levels can contribute to sirtuin mediated deacetylase-dependent alterations in both mitochondrial electron transport activity (resulting in increased production of reactive oxygen species, ROS) as well as to increased nuclear DNA damage leading to the activation poly-ADP-ribose polymerases (PARP)

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Natural compound found endogenously in human plasma and tissues Multiple mechanisms collagen synthesis, antioxidant, gene regulation Well-tolerated excellent safety profile in clinical studies Medical supervision requires physician oversight for optimal protocols Speak With a Physician 8-12wks Typical treatment duration to observe visible tissue remodeling and regenerative effects 3x/wk Standard dosing frequency for subcutaneous administration (varies by protocol and goals) GHK-Cu is unique because its a naturally occurring compound in human plasma that declines with age