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While traditional sleep aids force sedation by suppressing neural activity and often disrupt natural sleep architecture (particularly REM sleep), DSIP supports the bodys endogenous sleep-regulating systems to promote natural, restorative sleep with proper progression through all sleep stages
They can cause zinc deficiency with long-term use, so talk to your medical provider before starting a new supplement
Cellular debris was removed by centrifugation at 10,000g and 4 C for 10 min
The research was supported by grants from the National Science Foundation (EF-1038593, DMS-0943760) and the National Institutes of Health (R01 ES019876).
The BIOM file output from the DADA2 pipeline and the DECIPHER-aligned FastTree phylogenetic tree were input into QIIME (v1.9.1) and the scripts in the Supplementary Materials (QIIME Scripts compilation) were used to establish the alpha diversity metrics of Chao1 richness estimate, Simpsons evenness measure E, Shannon diversity index H, Simpsons diversity index, and Faiths phylogenetic diversity metric (whole tree) as well as the beta diversity measures of unweighted and weighted UniFrac analyses (the latter of which factors in ASV abundance 37 ) and BrayCurtis dissimilarity analysis
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