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They work as GLP-1 receptor agonists that mimic the feeling of fullness or satiety
Research suggests that while both forms of semaglutide have similar effects on the body, the way they are taken may change the experience of side effects: Lower Gastrointestinal Symptoms : Some studies suggest that sublingual semaglutide may lead to fewer gastrointestinal issues, like nausea or diarrhea, compared to injections
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Adriaenssens AE, Biggs EK, Darwish T, Tadross J, Sukthankar T, Girish M, Polex-Wolf J, Lam BY, Zvetkova I, Pan W, Chiarugi D, Yeo GSH, Blouet C, Gribble FM, Reimann F
Conclusion Nausea is a common but manageable side effect of GLP-1 agonists
Many plans already use some combination of eligibility criteria, documentation requirements, step therapy, or exclusions
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