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Autophagy as a common pathway in amyotrophic lateral sclerosis

Research in animal models has documented increased longitudinal bone growth in young subjects (PMID: 10373343) and increased bone mineral content (BMC) due to increased volume of bone, though bone mineral density itself remained unchanged (PMID: 10828840)

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Months 2 to 3: Visible changes in body composition typically modest fat loss around the midsection and improved muscle tone in active patients