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Adding more water creates a less concentrated mixture, while adding less water creates a more concentrated mixture
For a 250 mcg dose, this requires drawing 0.1 mL (10 units on an insulin syringe) of the reconstituted solution
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Split dosing protocols Some protocols divide the daily dose into morning and evening administrations
No special preparations are usually required, although some medications that increase bruising might be best avoided
If B12 levels are already normal, additional B12 is unlikely to improve fatigue
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