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Glutathione Disulfide Reductase (GSR) , also known as glutathione reductase (GR), catalyzes the reduction of glutathione disulfide (GSSG) to glutathione (GSH) in the presence of NADPH and flavin adenine dinucleotide (FAD)

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[6] [8] Animal studies [edit] GPX1 helps to prevent cardiac dysfunction after ischemia-reperfusion injuries