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Similarly, PPAR- has been shown to activate by PFAS in both animal and cell experiments, driving mesenchymal stem cells towards adipogenesis rather than osteogenesis and pre-adipocyte differentiation into adipocytes, thus resulting in imbalances in skeletal and adipose development and significant elevations in triglyceride levels [79,80,81,82]

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Hum Mol Genet 8:14511460 Reaume A, Elliott J, Hoffman E et al (1996) Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

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