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In addition, when used in combination with DOX at sublethal concentrations, a reduction in IC 50 is observed, representing an increase in the net antitumor activity of the drug ( in vitro , P2Et is cytotoxic both in resistant lines with the expression of Pgp + and in Pgp-lines in 2D and 3D cultures ( C
the cell lines ALL-SIL, HPB-ALL, P12-ICHIKAWA, and TALL-1 were kindly provided by Dr
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NMR 73 , 305317 (2019)
Importantly, ferroptosis has been proven to be a common intervention target for halting DKD progression (187)
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