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Copper in its metallic state has no effect on the skin and it becomes a potential irritant or allergen when it is corroded to become soluble through the action of exudates encountered on the skin surface, or in a relatively corrosive physiological environment such as the oral cavity or the uterus 3
Although it is available as a troche and as an injection form, those who want to realize the greatest results will find that they are achieved using the injection form
PMID: 16352683 Henninge J, et al
Urology 1986
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