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Combination treatment of b-AP15 with IAP antagonists is synergistic in HNSCC in vitro Given that our data suggests that XIAP plays a key role in regulating b-AP15-mediated anti-proliferative and pro-apoptotic effects, we hypothesised that combinatory treatment with b-AP15 and an XIAP inhibitor may be synergistic in HNSCC cells
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Calculate the true cost of discarding partially-used vials versus the risk of reduced potency from extended storage
Anti-Inflammatory Pathway Overlap Each compound has reported anti-inflammatory effects through different pathways in preclinical models
It does not support treatment beyond 24 weeks
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