All other data can be found within the main text, Supplementary information or Source Data files
Insufficient stomach acid Stomach acid, aka hydrochloric acid, plays an important role in releasing vitamin B12 from the proteins in food, which is later on absorbed through the intestine
coli formate dehydrogenase H gene directed Sec incorporation rather than termination, and that a dedicated suppressor tRNA encoded by selC was responsible [16, 17]
Do not adjust dosing or add additional compounds during this period
Some users experience anxiety, irritability, and mood changes that worsen over the treatment period
If you miss a dose entirely, therapeutic concentration drops noticeably by day three to five, with most patients experiencing returning appetite around day four or five as plasma levels decline below the effective threshold