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A Eli Lilly lanou o princpio ativo com o nome de Mounjaro para diabetes , rivalizando com o Ozempic
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5,6 In multidrug-resistant HL60/VCR acute myelogenous leukemia cells, GST is found to be expressed at higher levels than HL60
In addition, RNF4 mediates the proteasomal clearance of SUMOylated post-replicative DNA protein crosslinks (DPCs), including TOP1/2- and DNMT1-DPCs which are induced by topoisomerase poisons or hypomethylating agents 20,28,29
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