On/off cycling here is driven by caution, not by tolerance data: because there is no long-term human safety record, building in scheduled off periods is the conservative research default
Unlike caloric restriction alone, which often results in both fat and muscle loss, the peptides mechanism specifically targets adipose tissue without promoting protein catabolism
Aside from that, B12 shots also have higher absorption rates than oral supplements, most of which are lost to urine
Make sure you're hitting adequate protein and nutrients - the appetite suppression from semaglutide can make it easy to under-eat protein
Your doctor will provide specific recommendations
Researched for weight loss, joint pain & osteoarthritis, and visceral fat reduction