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Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin as monotherapy in patients with type 2 diabetes mellitus

You're Eating Less, Yay!But There IS A Downside Often, because you aren't hungry and you are eating less, you don't get enough nutrients to keep your body healthy

Glycemic control with diet, sulfonylurea, metformin, or insulin in patients with type 2 diabetes mellitus: progressive requirement for multiple therapies (UKPDS 49)

Position 34 substitution: Like liraglutide, lysine at position 34 was replaced with arginine to control where the fatty acid attaches

As your muscle mass increases, your basal metabolic rate rises, helping you burn more calories at rest