Their effects on GLP-1 are subtle compared to pharmaceutical options
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The body naturally produces glucagon-like peptides, which are made up of 30 amino acids, to aid in the digestion and absorption of the foods we eat, regulate appetite, manage blood sugar levels, and contribute to overall metabolic homeostasis
doi: 10.7759/cureus.88216 Summary Keywords GLP-1 receptor agonists, insulin resistance, metformin, myoinositol, network meta-analysis, obesity, polycystic ovary syndrome Citation Omarion A, Ayasa Y, Omarion Z, Jayouse B and Ayesh H (2026) Comparative analysis of glucagon-like peptide-1 receptor agonists, metformin, and inositol in improving anthropometric and metabolic outcomes in women with polycystic ovary syndrome: a network meta-analysis
In the commercial market, GLP1 prescription volume grew from 680,000 in January 2020 to 4.7 million in May 2025
Final FDA action on KPV is still pending. These updates concern compounding access for the individual ingredients