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Because it is newer, there is less flexibility and less long-term data on optimal maintenance dosing

GLP-1 was discovered in the 1980s, and GLP-1RAs have been around for about 20 years (the first one approved for humans was a synthetic version of a molecule isolated from the venom of Gila monsters), but recent development of new versions of this type of drug are revolutionising treatment of diabetes and obesity

IDegLira was also indirectly compared to alternative strategies of glycemic control intensification in patients with T2DM treated with basal insulin [29]

Its active ingredient is semaglutide, which is a GLP-1 receptor agonist (GLP-1 RA)

International Probiotics Association