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The immune cells in these patients are dealing with such an extreme, unrelenting burden of oxidative stress and mitochondrial lipid damage that they have frantically ramped up their own internal glutathione production in a desperate attempt to survive
Colon tissues with visible lesions were carefully fixed in 10% neutral buffered formalin for subsequent hematoxylin-eosin (H&E) and alcian blue-periodic acid-Schiff (AB-PAS) staining
This matters because glutathione exists in two states within your body, and the reduced form (GSH) represents the metabolically active version that actually performs anti oxidative stress functions
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