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A study based on Nrf2-KO (knockout of Nrf2) diabetic mice showed that syringaresinol inhibits pyroptosis caused by NLRP3/Caspase-1 in DN by activating the Nrf2/HO-1 signaling pathway [72]
Higher iLISI values indicate greater local mixing of cells from different datasets
Vitamin C supports collagen production and immune function
nevertheless, no statistically significant difference in weight was observed at the 8-week endpoint between the two groups (42)
AP-1, Activator Protein 1
10.3390/cells12091273 64 EnklaarT.BrixelL
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