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These include inhibiting the JAK2STAT3 signaling pathway, reducing GFAP expression, blocking inflammatory pathways such as NF-B, regulating neurotransmitter secretion such as GABA and modulating APOE expression to control astrogliosis 81,137,138
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Encourage patients to carry a source of simple sugar (e.g., glucose tablets) with them at all times to address hypoglycemic episodes when away from home
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This transition requires careful medical supervision, as stopping insulin while starting a GLP-1 drug involves monitoring for hyperglycemia during the switch period
Some 23 percent experienced a 75 percent reduction in migraine days per month
