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Modulation of Inflammatory Pathways GLP-1 receptor agonists work through sophisticated anti-inflammatory mechanisms: Modulation of the nuclear factor-kappa B (NF-B) pathway Reduction of inflammatory cytokine production Attenuation of oxidative stress Activation of the cAMP-PKA-dependent signaling pathway, which is crucial for anti-inflammatory effects 3

Howe S, Zphel D, Subbaraman H, Unger C, Held J, Engleitner T, et al

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