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they are prepared by licensed compounding pharmacies under federal compounding regulations
Hu Q, Zhang Y, Lou H, Ou Z, Liu J, Duan W, et al
10.1186/s12876-016-0432-5 19 KlaunigJ
The mechanisms most cited in the literature are promotion of angiogenesis (new blood-vessel formation, linked to VEGFR2 signaling), modulation of growth-factor and nitric-oxide pathways, and interaction with the gut-brain axis