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Clostridium butyricum and its metabolites regulate macrophage polarization through miR-146a to antagonize gouty arthritis

To address this problem, we propose that existing experimental data can be used to train machine learning (ML) models that are able to extrapolate in sequence space to accurately predict the activity of novel multi-specific peptide analogues

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Safety findings were consistent with the incretin drug class

However, pemvidutide showed a NASH reduction signal (reduction in liver fat) in an earlier Phase 1b trial interim analysis