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15,276 The activation of GLP-1R is linked to decreased NF-B pathway activity Treatment with GLP-1RAs can effectively mitigate chondrocyte apoptosis caused by endoplasmic reticulum stress and alleviate the associated inflammatory response
Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes: a randomised, placebo-controlled and active comparator-controlled phase 2 trial
32 , S269S272 (2009)
Effects are usually seen within 24 weeks, depending on injury severity
BPC-157 supports the remodeling phase, which begins at approximately 3 weeks post-op and continues for months