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It suppresses the IL-6/STAT3 pathway, thereby preventing the HCC cells from inhibiting the cytotoxic effect mediated by natural killer cells (NKs) ( + T cells and induce immunity to tumor rechallenge in Hepa16 allograft mice ( pos CD3 + T cells treated with exendin-4 secreted less IFN-, exhibited weaker migration ability, and upregulated genes related to apoptosis, immunoregulation, and immune deficiency, such as CASP3 and CASP7

IUBMB life 60 , 790797, doi: 10.1002/iub.124 (2008)

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On the heels of their initial findings, the group began to wonder about glutathiones impact in the ER, which works with the mitochondria to keep the cell in a state of homeostasis

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