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This pattern holds biological significance in PD in that it suggests that disease- or treatment-related effects may exert selective pressure on the microbial network in the gut without necessarily lowering the overall number of microbial species present, thereby exerting an influence on GBA signaling and L-DOPA metabolism

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However, it is not a required side effect

studied for cravings, little proven effect [8] Guarana: included for energy

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