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Figure 5 3 Metabolic targeting strategies in GBM 3.1 Ketogenic diet as a metabolic therapy Recently, the ketogenic diet (KD) has attracted considerable scientific attention as a potential adjuvant therapy for GBM (among other cancers) alongside standard treatment (85, 86)

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Hippo signaling pathway The Hippo pathway is a conserved regulatory cascade that controls tissue size, cell proliferation, apoptosis, stemness, and regeneration by modulating the subcellular localization of Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ)