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However, they commonly cause gut side effects like indigestion, nausea, vomiting and diarrhoea
Notably, p53 activates PCDHB14 and inhibits SLC7A11 expression by enhancing p65 protein ubiquitination-mediated degradation, thereby abrogating p65 bind to the SLC7A11 promoter (Zhao et al., 2022)
The article says severe or persistent stomach cramps warrant immediate provider contact, especially when accompanied by vomiting, diarrhea, or signs of pancreatitis
Dehydration becomes a concern if vomiting persists, so drinking electrolyte-containing beverages and monitoring your fluid intake helps prevent complications
Mild improvement in skin texture 4
However, in older adults or those with sarcopenia, functional assessment (using tools like grip strength measurement or the SARC-F questionnaire) is warranted to identify patients who may need additional intervention to preserve muscle function
