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This was used either as a fixed dose (staying at 4mg throughout) or as a faster escalation route to 8mg

A Super Bowl commercial put out by the telehealth company Hims & Hers is drawing heat from critics who say the company's promotion of its weight-loss drugs misled consumers by leaving out key information

Additionally, some patients may need to discontinue use due to significant side effects

But the few bad actors in the market can cause real harm

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Briefly, under anesthesia induced by intraperitoneal (i.p.) injection of ketamine (80 mg/kg) and xylazine (10 mg/kg), rats were exposed to octave-band noise (816 kHz) at 108 dB SPL for 2 h