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Zhou Q, Li S, Li M, Ke D, Wang Q, Yang Y, et al

More recent work linked long-term NS work ( 10 years) to significant hypomethylation in 85 CpG sites, including loci in ZFHX3, a gene involved in circadian rhythm regulation and tumor suppression, and ATXN7, associated with transcriptional control and cancer susceptibility 231

Although biologically notable, transcriptomic shifts do not necessarily indicate tissue rejuvenation or restored function in humans

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Brown, so they may prefer taking it on the weekend when they can stay home rather than during their work week