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Subsequently, DP breaks cysteinyl glycine into cysteine and glycine, which are reabsorbed into the cell to engage in a novel GSH synthesis pathway (summarized in Fig

Similarly, cGMP-mediated pathways that promote long-term potentiation in the hippocampus may yield opposing effects in other circuits, depending on nitric oxide signaling and phosphatase activation

Understanding which combinations produce additive versus truly synergistic effects guides evidence-based protocols

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