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SFN is also shown to reduce proteolytic stress by decreasing MMP-9 expression and preserving BBB, and it also elevates the concentration of anti-inflammatory cytokine IL-10 in experimental autoimmune encephalomyelitis in C57BL/6 mice (88)

Comparing photos at 8-12 week intervals typically reveals more obvious changes than shorter comparison windows

They begin at the cellular level due to oxidative stress, excess melanin production, inflammation, and reduced collagen activity

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EGCG is a type of plant compound called a catechin

Archives of biochemistry and biophysics, 503(1), 41-53