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In humans, many circadian-regulated rhythms exhibit attenuated amplitude and phase shifts in older age (Panagiotou et al., 2021)

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If it sat in a warm car for several hours or was exposed to temperatures above 30C for any significant period, the medication safety and potency are compromised

It has been investigated in preclinical studies for its potential cytoprotective, angiogenic, and regenerative properties across multiple tissue types