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As of December 2025, there are no peer-reviewed trials directly examining whether a GLP-1 agonist helps or harms exercise performance in athletes
Certain individuals should avoid semaglutide
On the surface, this seems like a logical choice
Medications like semaglutide should be refrigerated between 36F and 46F (2C to 8C) before first use
In rare cases, acute hepatitis B can cause liver failure
Results typically seen within weeks with increased results over time
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