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In the Phase IIb trial data summarized by Metabolic Pharmaceuticals, participants receiving up to 1 mg/day of oral AOD-9604 for 24 weeks showed no statistically significant changes in fasting glucose, insulin, or IGF-1 compared to placebo [6]

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As noted by the American Association for the Study of Liver Diseases (AASLD): "Drug-induced liver injury remains a diagnosis of exclusion, and re-challenge with the suspected agent should be avoided in cases of serious hepatotoxicity" [8]

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