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impaired cholinergic transmission is the hallmark of Alzheimers disease [34, 35]

You're hitting mitochondrial health from two angles simultaneously: MOTS-C improves mitochondrial efficiency and increases fat oxidation NAD+ replenishes the coenzyme required for ATP synthesis For anyone over 40 who's training seriously, this pairing addresses two of the most significant age-related performance bottlenecks at once

Reference: Chen, T.-H., Wang, H.-C., Chang, C.-J., & Lee, S.-Y

481,482,487,488 It is also associated with intradialytic hypotension in patients receiving HD