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On one hand, targeted induction of ferroptosis presents a powerful strategy to eliminate tumor cells, particularly those resistant to apoptosis, and can synergize with standard chemotherapeutics like gemcitabine to overcome treatment resistance
Modular DNA nanodevice agonists (DNDA) achieve selective uptake by macrophages through precise self-assembly, releasing cGAS-recognizing fragments intracellularly to activate the cGASSTING pathway, thereby synergizing with immune checkpoint blockade to exert antitumor effects (280)
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Different modalities of renal replacement therapy using standard dialysis criteria, such as CVVH, CVVHD, CVVHDF, and IHD have been
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