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3.1 Metformin activates AMPK to inhibit the platelet-derived growth factor (PDGF) pathway The PDGF signaling pathway is one of the most characteristic pathways in HSC activation

doi: 10.1016/j.semcdb.2016.11.008 69 ZhangSTeoKYWChuahSJLaiRCLimSKTohWS

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Results and Discussion Isolation and Characterization of Marker Compounds Isolation of marker compounds viz, diosgenin, charantin, and hydroxychalcone were done as per the procedure given in Section Isolation of Marker compounds

Exosomes harbour bioactive chemicals that indicate specific physiological conditions, modulate bioenergetic metabolism, and facilitate tissue healing