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We do have: 10+ year safety data for earlier GLP-1 agonists (liraglutide, exenatide) Growing evidence of cardiovascular benefits from weight loss medications Understanding that obesity itself has well-documented health risks The risk-benefit calculation often favors treatment, but this is an individual decision that should be made with your healthcare provider based on your specific medical situation
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The nature and severity of the muscle spasms and twitching, likely on mechanism, remains unclear
However, these patients should be monitored for any unexpected effects, and dose titration should proceed cautiously