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Of the affected genes, 59% were upregulated (made more active) and 41% were downregulated (made less active)
Inducible NOS, iNOS The major functions of NO production through activation of iNOS are associated with the bactericidal and tumoricidal actions of macrophages
Limitations of Current Treatments Doctors rely on immunosuppressive drugs, corticosteroids, and biologic therapies to manage autoimmune disease
Rodent models, generally rats and mice, are the most common
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