Administered once a week, this option showed impressive results during trials, with participants losing an average of 20.9% of their body weight at the highest dose
The article also discusses the evolving evidence on GLP-1s and mental health, noting that while some studies have reported reductions in depressive symptoms, data remain limited and careful patient selection is still recommended
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That is on par with a reduction seen with a dedicated anti-hypertensive medication and does probably explain some of the complaints of dizziness and hypotension
Other reported effects Beyond GI symptoms, clinical trials noted several other effects worth monitoring: Increased heart rate: A small, dose-dependent increase in resting heart rate was observed, consistent with what occurs with other GLP-1 agonists
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