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For immunohistochemistry, the following primary antibodies were applied: anti-albumin (# ab192603, Abcam

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(IV) The metal nanomedicines show great potential for cancer therapy not only because of the capability of GSH exhaustion, but also for their wide range of other biological effects, such as interference with osmotic pressure, regulation of the immune system, and activation of biocatalysis ( in vivo metabolism and excretion behavior of metal nanomedicines should also be conducted

Defining the moribund condition as an experimental endpoint for animal research