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This drives de novo blood vessel formation angiogenesis into injured tissue, which is a prerequisite for sustained repair and regeneration
3.5.2 Activation of the Keap1Nrf2 pathway and detoxification ITCs are potent activators of the Keap1Nrf2 signaling pathway, which upregulates cytoprotective genes
While not FDA-approved for longevity enhancement, its used in supervised medical protocols for healthspan optimization and biological age management
In the phase 2 trial published in the New England Journal of Medicine (Jastreboff et al.), participants on the 12mg dose achieved a mean weight reduction of 24.2% at 48 weeks
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