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Sayed SF, Ahmed I
Note: Results vary greatlysome feel nothing, others swear by it
Detection of dual TEL-ABL transcripts and a Tel-Abl protein containing phosphotyrosine in a chronic myeloid leukemia patient
Its large size may affect native conformation remove with specific proteases (PreScission, thrombin) after purification for structural/functional studies
Frequency: The frequency of administration is typically once daily, although the available data is limited
Titration pacing matters In the Phase 2 NEJM trial, GI side effect rates nearly doubled when participants jumped to 8 mg instead of climbing gradually from 1-2 mg
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