Considering the network that bi-directionally links obesity and insulin resistance in the pathogenesis of PCOS, it seems to be particularly appealing a new approach producing, at the same time, satisfactory and permanent weight loss, improvement in insulin resistance and in metabolic profile, with additional favourable outcomes on reproductive and cardiovascular systems (19)
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Beyond addressing sudden weight gain, these medications can help ease VMS, offering relief from hot flashes and night sweats
The functions of butyrate can also be mediated through the inhibition of HDACs