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GLP-1 receptor agonists semaglutide (Ozempic/Wegovy), tirzepatide (Zepbound/Mounjaro) are genuinely impressive drugs

In studies with rodents, Ozempic and medicines that work like Ozempic caused thyroid tumors, including thyroid cancer

Semaglutide, in any form, is a prescription medication that must be evaluated, prescribed, and monitored by a licensed provider

Project administration: Motoko Yanagita

mRNA levels were determined using TaqMan probes for fatty acid binding protein 4 ( Fabp4 , Mm00445878_m1), perilipin-2 ( Plin2 , Mm00475794_m1), aryl hydrocarbon receptor nuclear translocator-like protein 1 (Arntl, Mm00500223_m), semaphorin 3 C ( Sema3c , Mm00443121_m1) and hypoxanthine phosphoribosyltransferase 1 ( Hp rt, Mm03024075_m1) in custom-made low density array cards (Thermo Fisher) or in single assays on a QuantStudio 7 Real-Time PCR system

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