10.1038/s41586-018-0104-4 115 PiccaA.CalvaniR.Coelho-JuniorH
Many patients begin to see significant weight loss within the first month of treatment
GLP-1RAs alleviate liver injury by inhibiting hepatocyte apoptosis and promoting the TFEB-dependent transcription of lysosome-related genes, which stimulates hepatocyte autophagy to prevent lipid accumulation (Zhou et al., 2020
And get a quick vitamin shot while you're at it
Zafereo ME , McIver B, Vargas-Salas S, Domnguez JM, Steward DL, Holsinger FC, Kandil E, Williams M, Cruz F, Loyola S, Solar A, Roa JC, Len A, Droppelman N, Lobos M, Arias T, Kong CS, Busaidy N, Grubbs EG, Graham P, Stewart J, Tang A, Wang J, Orloff L, Henrquez M, Lagos M, Osorio M, Schachter D, Franco C, Medina F, Wohllk N, Diaz RE, Veliz J, Horvath E, Tala H, Pineda P, Arroyo P, Vasquez F, Traipe E, Marn L, Miranda G, Bruce E, Bracamonte M, Mena N, Gonzlez HE
The FDA guidelines (for women, which clinicians also follow for men) say no more than one dose in 24 hours, and no more than 8 doses per month